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Butalbital chemical structure
Butalbital
Systematic (IUPAC) name
5-(2-methylpropyl)-5-(2-propenyl)-
2,4,6(1H,3H,5H)-pyrimidinetrione
Identifiers
CAS number 77-26-9
ATC code ?
PubChem 2481
DrugBank APRD00266
Chemical data
Formula C11H16N2O3
Mol. weight 224.256
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Half life about 35 hours[1]
Excretion ?
Therapeutic considerations
Pregnancy cat.
?
Legal status
Schedule III(US)
Routes ?
Butalbital, 5-allyl-5-isobutylbarbituric acid, is a barbiturate with an intermediate duration of action. It has the same chemical formula as talbutal but a different structure. Butalbital is often combined with other medications, such as acetaminophen or aspirin, and is commonly prescribed for the treatment of pain and headache. The various formulations combined with codeine are FDA approved for the treatment of tension headaches.
Combinations include:
* butalbital and acetaminophen (Axocet®, Bucet®, Bupap®, Cephadyn®, Dolgic®, Phrenilin®, Phrenilin Forte®, Sedapap®)
* butalbital, acetaminophen, and caffeine (Fioricet®, Esgic®, Esgic-Plus®)
* butalbital and aspirin (Axotal®)
* butalbital, aspirin, and caffeine (Fiorinal®, Fiormor®, Fiortal®, Fortabs®, Laniroif®)
* butalbital, acetaminophen, caffeine, and codeine phosphate (Fioricet #3 with Codeine®) (Fioricet w/ Codeine®)
* butalbital, aspirin, caffeine, and codeine phosphate (Fiorinal #3 with Codeine®) (Fiorinal w/ Codeine®)